S. Maria della Misericordia University Hospital



Center for Parkinson’s Disease & Movement Disorders

Section of Neurology


Loc. S.Andrea delle Fratte 06156 Perugia


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The Center for Parkinson’s Disease and Movement Disorders of Perugia provides diagnosis, treatment and support for patients with Parkinson’s disease and movement disorders with a multidisciplinary team of dedicated neurologists, neuropsychologists, physiatrists, specialized nurses, neuroradiologists, neurosurgeons, gastroenterologists and geneticists.


Approximately 30 movement disorders outpatient visits are scheduled every week (about 1400 patients examined yearly). Patients with movement disorders can be admitted in the Neurology ward (total: 20 beds) for diagnostic and therapeutic purposes, including management and treatment of complicated phases.


In cooperation with “Unione Parkinsoniani Perugia”, the Center promotes programs of physical activities, psychological training, speech and occupational therapy tailored according to the disease stage. The Center also promotes education for general practitioners, neurologists and nurses with courses and seminars open also to patients and caregivers.


Clinical and preclinical research is carried out in collaboration with national and international centers and is mainly focused on: i) diagnostic and prognostic role of CSF biomarkers, in particular alpha-synuclein; ii) seeding aggregation assays; iii) assessment of the impact of alpha-synuclein oligomers on synaptic plasticity in animal models.

Diagnostic procedures

1.5 and 3T MRI

Nuclear Medicine exams (PET, DaT Scan, MIBG)

CSF analysis of amyloidosis, tauopathy, neurodegeneration and inflammation biomarkers

Neuropsychological evaluation

Neurophysiological evaluation

Physiatric evaluation

Services and treatments provided

Neurological visits

Physical therapy

EMG- and ultrasound-guided botulinum toxin treatment

Genetic evaluation and rare diseases certification

Phoniatric evaluation

Individualized rehabilitation programs

Deep Brain Stimulation and infusional therapies

Useful numbers

Out-patient reception


Hospital booking service for visits at the Movement Disorders Center through the public healthcare system



Hospital booking service for access by payment at the Movement Disorders Center


Contact person for patients

Marta Ferrettini



Medical Personnel

Lucilla Parnetti, MD, PhD, Professor of Neurology, Head of the Neurology Section

Nicola Tambasco, MD, PhD – Neurologist, Responsible of the Movement Disorders Center

Simone Simoni, MD – Neurologist

Pasquale Nigro, MD – Neurologist

Federico Paolini Paoletti, MD – Neurologist

Marta Filidei, MD – Neurology Resident

Giulia Cappelletti, MD – Neurology Resident

Neuropsychology and Psychology Personnel

Elena Chipi – Psychologist

Nicola Salvadori – Psychologist

Chiara Montanucci – Psychologist

Physical therapy Personnel

In collaboration with Unione Parkinsoniani Perugia and Centro Ospedaliero di Riabilitazione Intensiva (C.O.R.I.) di Passignano sul Trasimeno (Perugia)

Specialized nurses devoted to parkinsonian patients

Ilario Moscara, RN

Michela Pelucchini, RN

Research Personnel

Alessandro Tozzi, PhD, Professor of Physiology

Massimiliano Di Filippo, MD, PhD, Professor of Neurology

Giovanni Bellomo, PhD, physicist

Miriam Sciaccaluga, PhD

Andrea Mancini, MD, Neurologist, PhD student

Alfredo Megaro, PhD student

Laura Bellingacci, PhD student

Simone Simoni, MD, PhD student

Pasquale Nigro, MD, PhD student

The other Centers of Fresco Network

Villa Margherita Rehabilitation Center

Arcugnano, Vicenza


Center for Parkinson’s Disease and Movement Disorders

“Moriggia-Pelascini” Hospital

Gravedona ed Uniti, Como


Rehabilitation Department for Parkinson’s Disease and Severe Acquired Brain Injury

IRCCS Ca’ Granda Policlinic Hospital



Center for Parkinson’s Disease and Movement Disorders

IRCCS Policlinic Hospital San Martino



Center for Parkinson’s Disease and Movement Disorders

S. Chiara University Hospital



Regional Referral Center for Parkinson’s Disease

International centers

University Hospital Würzburg

The Parkinson’s Disease and Movement Disorders Center – Department of Neurology